the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
#dosing-titration 2025-02-15
Saturday22 messages5 participantstimes are UTC
Highlights from this day
- seizure_letter — the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess 07:08
- fasting_insulin — update on the earlier thing a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored 07:12
- fasting_insulin — appetite returning at the end of the week is extremely common and is not the dose failing 08:09
- rotate_the_site — the trials escalated on a fixed schedule because a trial has to. you are not a trial 09:43
- bac_water_bill — if you are going up because the scale stalled for two weeks, wait. two weeks is noise 11:35
unrelated but nobody here can tell you what dose to be on and the ones who try get corrected
update on the earlier thing a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored
wk 1-4 0.25mg
wk 5-10 0.50mg (held 2 extra weeks)
wk 11-14 1.00mg
wk 15-26 1.70mg (held, long)
wk 27+ 2.40mg💀13
half life is a week
if it "stopped working after four days" that is almost never pharmacokinetics
appetite returning at the end of the week is extremely common and is not the dose failing
[edited]wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)came down from a treatment dose to maintenance over about three months and it was uneventful
ok so the people who do best here are almost always the ones going slowest
hold
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i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
do you count from injection day or from when you actually felt it
does a missed week reset anything or do you just carry on
has anyone gone up and then straight back down and been glad they tried
the trials escalated on a fixed schedule because a trial has to. you are not a trial
👀1
is there a trial anywhere that studied twice weekly, or is it all anecdote
pick a day and stick to it
held for months
two weeks is nothing
😂3
i escalate on symptoms. if the current dose is still doing something i stay on it
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
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i drifted from sunday to wednesday over a year and only noticed when i checked the log