i drifted from sunday to wednesday over a year and only noticed when i checked the log, someone check my working
#dosing-titration 2025-03-02
Sunday22 messages5 participantstimes are UTC
Highlights from this day
- apob_over_ldl — appetite returning at the end of the week is extremely common and is not the dose failing 18:21
- pin29g — coming back to this how do you decide between holding and stepping when both feel wrong 18:26
- pin29g — quick one the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess 18:59
- vacuum_vic — if i took it 7 days late do i shift the schedule or go back to the old day 20:26
- nhs_pathway_nell — does a missed week reset anything or do you just carry on 20:45
if i hold at 2 indefinitely am i losing anything
appetite returning at the end of the week is extremely common and is not the dose failing
👍8🧪1🧊2
hold
[edited]🧪1
coming back to this how do you decide between holding and stepping when both feel wrong
🙏10👍1
with a roughly seven day half-life you are near steady state after about five weeks at a dose, your mileage will differ
right so if you are asking whether to go up, the fact you are asking usually means not yet
quick one the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
i went from 1 to 10 and honestly could not tell the difference in appetite
if you are going up because the scale stalled for two weeks, wait. two weeks is noise
came down, no regrets
n of 1
i escalate on symptoms. if the current dose is still doing something i stay on it
🙏2
held for months
is there any actual reason to escalate every 4 weeks other than the trial did it
[edited]if i took it 7 days late do i shift the schedule or go back to the old day
📈9
if it "stopped working after four days" that is almost never pharmacokinetics
the ladder in the trials is a starting point, not a schedule you owe anyone
does a missed week reset anything or do you just carry on
lot-log.csv
342 rows · not retained in the public archive
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
[edited]i hold for two months minimum before i decide a dose has stopped doing anything