#dosing-titration 2025-03-12

Wednesday11 messages4 participantstimes are UTC

Highlights from this day

step_one_sian — i drifted from sunday to wednesday over a year and only noticed when i checked the log 19:56
step_one_sian — is week 26 too early to be thinking about the next step 20:20
step_one_sian — appetite returning at the end of the week is extremely common and is not the dose failing 20:24
step_one_sian — follow up with a roughly seven day half-life you are near steady state after about five weeks at a dose 20:25
step_one_sian — split dosing has no trial behind it. people here do it and report on it, thats all 20:41

i drifted from sunday to wednesday over a year and only noticed when i checked the log

is week 26 too early to be thinking about the next step

🤝13

i would hold

appetite returning at the end of the week is extremely common and is not the dose failing

[edited]

follow up with a roughly seven day half-life you are near steady state after about five weeks at a dose

💀13

my dose day has drifted 7 days later over 4 months, does it matter

came down, no regrets

wk 1-4    2.5mg
wk 5-8    5.0mg
wk 9-20   7.5mg   <- stayed here
wk 21-24  10.0mg  (no extra benefit for me)
wk 25+    7.5mg   (came back down)

split dosing has no trial behind it. people here do it and report on it, thats all

too early imo

thats normal

i escalate on symptoms. if the current dose is still doing something i stay on it