pick a day and stick to it
#dosing-titration 2025-03-27
- never_for_sale — after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice 13:06
- never_for_sale — stepping back down on purpose is a completely reasonable move and this channel should say so more often, anyway 13:13
- never_for_sale — is there any actual reason to escalate every 4 weeks other than the trial did it the ladder in the trials is a starting point, not a schedule you owe anyone 14:31
- split_dose_sam — the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess, ask me again in a month 16:24
i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
i went from 2.4 to 10 and honestly could not tell the difference in appetite
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
appetite returning at the end of the week is extremely common and is not the dose failing
held for months
stepping back down on purpose is a completely reasonable move and this channel should say so more often, anyway
i drifted from sunday to wednesday over a year and only noticed when i checked the log
if you are asking whether to go up, the fact you are asking usually means not yet
end of week thing
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
is there any actual reason to escalate every 4 weeks other than the trial did it
the ladder in the trials is a starting point, not a schedule you owe anyone
whats the smallest step anyone has managed between doses
plateau versus set point is not answerable in under six months of data
came down, no regrets
the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess, ask me again in a month
nobody here can tell you what dose to be on and the ones who try get corrected
small steps are better than big ones and the only reason people take big ones is impatience
i would hold