vialroom

#dosing-titration 2025-07-08

Tuesday16 messages4 participantstimes are UTC
Highlights from this day
  • taper_tess — if you are asking whether to go up, the fact you are asking usually means not yet 05:23
  • identity_shift — after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice the trials escalated on a fixed schedule because a trial has to.… 09:14
  • reship_rita — i log dose, day, weight and one line about how the week felt. thats enough to make decisions on the ladder in the trials is a starting point, not a schedule you owe… 09:29
TT

the trials escalated on a fixed schedule because a trial has to. you are not a trial

IS

with a roughly seven day half-life you are near steady state after about five weeks at a dose

EE

i escalate on symptoms. if the current dose is still doing something i stay on it, anyway

the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess, thats just me

appetite returning at the end of the week is extremely common and is not the dose failing

TT

if you are asking whether to go up, the fact you are asking usually means not yet

fridge-temps.csv
650 rows · not retained in the public archive
EE

dose day drift is mostly harmless with a weekly compound, but pick a day and defend it

IS

you do not have to escalate at all. that is a real option that gets forgotten
small steps are better than big ones and the only reason people take big ones is impatience

my titration ladder took 11 months to climb and i would do it slower again

quick one i drifted from sunday to wednesday over a year and only noticed when i checked the log

RR

i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
the ladder in the trials is a starting point, not a schedule you owe anyone