Digest for the week of 2025-03-07 has been published.
#dosing-titration 2025-12-08
Monday19 messages5 participantstimes are UTC
Highlights from this day
- VialBot — Digest for the week of 2025-03-07 has been published. 20:50
- cedar_counts — is week 8 too early to be thinking about the next step my titration ladder took 26 months to climb and i would do it slower again 20:58
- oli_orals — i went from 7.5 to 10 and honestly could not tell the difference in appetite, happy to be corrected 22:39
whats the smallest step anyone has managed between doses
is week 8 too early to be thinking about the next step
my titration ladder took 26 months to climb and i would do it slower again
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does a missed week reset anything or do you just carry on
i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat
i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
update from 3 months ago: held at the same dose the whole time and still losing slowly
how long did you hold at 10 before you moved up
the honest answer is that most of us are running protocols nobody has ever studied
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
coming down from 12 to 10, how bad is the appetite rebound
is it normal for appetite to come back at the end of the week
i went from 7.5 to 10 and honestly could not tell the difference in appetite, happy to be corrected
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thats anecdote
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small steps are better than big ones and the only reason people take big ones is impatience
came down from a treatment dose to maintenance over about three months and it was uneventful, i think
is there a trial anywhere that studied twice weekly, or is it all anecdote
pick a day and stick to it