unrelated but if i hold at 2.4 indefinitely am i losing anything
#dosing-titration 2026-01-03
Saturday18 messages4 participantstimes are UTC
Highlights from this day
- a1c_lag — coming back to this what does the room think about jumping a rung to catch up 21:06
- a1c_lag — does a missed week reset anything or do you just carry on 21:24
- auckland_aliquot — ok so stepping back down on purpose is a completely reasonable move and this channel should say so more often 21:40
- a1c_lag — if the current dose is still working, going up is spending headroom you might want later, we shall see 21:59
- amsterdam_aliquot — split dosing has no trial behind it. people here do it and report on it, thats all 22:01
coming back to this what does the room think about jumping a rung to catch up
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
half life is a week
no trial for that
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my titration ladder took 24 months to climb and i would do it slower again
does a missed week reset anything or do you just carry on
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steady state is 5 weeks
thats noise
ok so stepping back down on purpose is a completely reasonable move and this channel should say so more often
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how do you tell a plateau from just being at your set point
while im here my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
i have been at 2 for 25 months and honestly i have stopped wanting to move
a missed week does not reset you, but going straight back to the top dose after a gap is how people get floored
if the current dose is still working, going up is spending headroom you might want later, we shall see
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split dosing has no trial behind it. people here do it and report on it, thats all
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held for months
auckland_aliquota missed week does not reset you, but going straight back to the top dose after a gap…
pick a day and stick to it