thats normal
#dosing-titration 2026-03-24
Tuesday38 messages9 participantstimes are UTC
Highlights from this day
came down from a treatment dose to maintenance over about three months and it was uneventful
not advice
for the archive is week 14 too early to be thinking about the next step
plateau versus set point is not answerable in under six months of data, happy to be corrected
too early imo
pick a day and stick to it
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do you count from injection day or from when you actually felt it
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i log dose, day, weight and one line about how the week felt. thats enough to make decisions on
update from 11 months ago: held at the same dose the whole time and still losing slowly
i drifted from sunday to wednesday over a year and only noticed when i checked the log
split dosing has no trial behind it. people here do it and report on it, thats all, not advice obviously
i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else
lot-log.csv
282 rows · not retained in the public archive
with a roughly seven day half-life you are near steady state after about five weeks at a dose
i went from 5 to 2 and honestly could not tell the difference in appetite
dose day drift is mostly harmless with a weekly compound, but pick a day and defend it
ok so if it "stopped working after four days" that is almost never pharmacokinetics, ask me again in a month
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the trials escalated on a fixed schedule because a trial has to. you are not a trial, still working it out
if it "stopped working after four days" that is almost never pharmacokinetics
whats the longest anyone has stayed on one dose
after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat
update on the earlier thing nobody here can tell you what dose to be on and the ones who try get corrected, happy to be corrected
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anyone here split their weekly into two and would they do it again
thats anecdote
peptidemeter-summary-g-0641.pdf
2 pages · 240 KB · not retained in the public archive
if you are going up because the scale stalled for two weeks, wait. two weeks is noise, thats just me
how do you decide between holding and stepping when both feel wrong
no trial for that
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update question: did anyone who held for 26 months regret it
Batch lookup B-0329: 3 independent reports on file, earliest 2025-06-01.
anyone tracked whether a smaller more frequent dose changed their side effects
i escalate on symptoms. if the current dose is still doing something i stay on it
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if the current dose is still working, going up is spending headroom you might want later
has anyone gone up and then straight back down and been glad they tried
thats noise
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i would hold
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how long did you hold at 1 before you moved up
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held for months
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whats a sensible maintenance dose after a year at treatment dose