thats normal
#dosing-titration 2026-05-15
Friday21 messages6 participantstimes are UTC
Highlights from this day
- ghk_gia — my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step 20:00
- luerlok — my dose day has drifted 8 days later over 1 months, does it matter 20:18
- u100_pat — i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, i have it written down somewhere 20:27
- u100_pat — is there any actual reason to escalate every 4 weeks other than the trial did it 20:47
- van_isle_vial — do you count from injection day or from when you actually felt it 21:49
while im here whats your rule for when a side effect means hold rather than push
appetite returning at the end of the week is extremely common and is not the dose failing
my rule: if a side effect is still there at day five, i hold. if it clears by day three, i step
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if i hold at 12 indefinitely am i losing anything
update question: did anyone who held for 8 months regret it
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my dose day has drifted 8 days later over 1 months, does it matter
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do you escalate on the calendar or on how you feel
end of week thing
go slower
steady state is 5 weeks
i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else, i have it written down somewhere
quick one is it normal for appetite to come back at the end of the week
unrelated but stepping back down on purpose is a completely reasonable move and this channel should say so more often
is there any actual reason to escalate every 4 weeks other than the trial did it
not advice
if it "stopped working after four days" that is almost never pharmacokinetics
pick a day and stick to it
i went from 5 to 2.5 and honestly could not tell the difference in appetite, from memory
i would hold
hold
do you count from injection day or from when you actually felt it
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