two weeks is nothing
#dosing-titration 2026-05-16
- hk_hplc — sorry to jump in after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice 17:54
- hk_hplc — you do not have to escalate at all. that is a real option that gets forgotten 18:06
- hk_hplc — the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess 18:35
came down, no regrets
held for months
sorry to jump in after a gap of more than about three weeks i restart one rung lower. thats my own rule, not advice
half life is a week
i went from 2.5 to 2.4 and honestly could not tell the difference in appetite, i could be wrong
i jumped a rung once to catch up after a supply gap and it was a bad week. would not repeat
with a roughly seven day half-life you are near steady state after about five weeks at a dose, for what its worth
you do not have to escalate at all. that is a real option that gets forgotten
not advice
stepping back down on purpose is a completely reasonable move and this channel should say so more often
end of week thing
thats anecdote
pick a day and stick to it
thats normal
how do you decide between holding and stepping when both feel wrong
the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess