if i took it 9 days late do i shift the schedule or go back to the old day
#dosing-titration 2026-06-30
Tuesday18 messages4 participantstimes are UTC
Highlights from this day
- ten_of_ten — i went up too fast and im paying for it, do i drop back or ride it out 11:52
- ten_of_ten — if you are asking whether to go up, the fact you are asking usually means not yet i escalate on symptoms. if the current dose is still doing something i stay on it 12:07
- lead_time_lars — dose day drift is mostly harmless with a weekly compound, but pick a day and defend it 12:33
i went up too fast and im paying for it, do i drop back or ride it out
wk 1-4 2.5mg
wk 5-8 5.0mg
wk 9-20 7.5mg <- stayed here
wk 21-24 10.0mg (no extra benefit for me)
wk 25+ 7.5mg (came back down)appetite returning at the end of the week is extremely common and is not the dose failing
my dose day has drifted 3 days later over 18 months, does it matter
does a missed week reset anything or do you just carry on
i went to the top of the ladder, felt no better than two rungs down, and came back. that is data for me and nobody else
if i hold at 5 indefinitely am i losing anything
if you are asking whether to go up, the fact you are asking usually means not yet
i escalate on symptoms. if the current dose is still doing something i stay on it
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dose day drift is mostly harmless with a weekly compound, but pick a day and defend it
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
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*week 23 not week 6
hold
i hold for two months minimum before i decide a dose has stopped doing anything
the argument for splitting is a flatter curve. the argument against is you have doubled your injections for a guess
the trials escalated on a fixed schedule because a trial has to. you are not a trial, someone check my working
do you escalate on the calendar or on how you feel
small steps are better than big ones and the only reason people take big ones is impatience, thats just me
thats normal
the people who do best here are almost always the ones going slowest