what does everyone actually mean when they say listen

steady state is 5 weeks

held there a while

sit on it

thats anecdote

hold

symptoms not calendar

in what sense, came down, no regrets

the label ladder exists because the escalation is what causes the sickness, not the dose itself

i went from 2.4 to 0.5 and honestly could not tell the difference in appetite, ask someone qualified about yours

accurate, day either side is noise

having sat on this a while the ladder in the trial was a tolerability schedule, not a target. everyone forgets that, that is my ladder not a recommendation

the last two weeks of a step tell you more than the first two, because the first two are still climbing, the trial schedule is not a target