#maintenance 2025-12-10

Wednesday14 messages4 participantstimes are UTC

Highlights from this day

ring_size_down — SURMOUNT-OSA is the stopping one. weight came back on for most people once the drug stopped. that is the finding, not an opinion 19:17
panel_before_after — i put 14 back on after stopping and then went back on it. it worked the same the second time round, thats one data point 19:27
panel_before_after — everybody i have seen stop and hold it did something else as well, without exception in my time here, take that with a pinch of salt 20:31
is_this_forever — how long did people stay at treatment dose after hitting goal 20:58

SURMOUNT-OSA is the stopping one. weight came back on for most people once the drug stopped. that is the finding, not an opinion

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*that should say weekly

did your maintenance dose end up higher or lower than you expected it to

thats fluctuation

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i put 14 back on after stopping and then went back on it. it worked the same the second time round, thats one data point

🔥4

protein up not down

how do people handle a two week holiday at a maintenance dose

genuine question i was wrong about maintenance being the easy part and i had said so loudly for a year beforehand, n of 1 obviously

everybody i have seen stop and hold it did something else as well, without exception in my time here, take that with a pinch of salt

resistance training two or three times a week is what the room converged on and it is not glamorous

how do you decide youre actually at maintenance rather than just stalled

is there any trial data at all on a lower frequency schedule

how long did people stay at treatment dose after hitting goal

m0  118.4
m1  113.9
m2  110.2
m3  108.8
m4  108.1  <- the stall
m5  105.0
m6  101.6
m7   99.2

set a trigger weight