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#oral-glp1 2025-08-09

Saturday39 messages9 participantstimes are UTC
Highlights from this day
  • step_one_sian — follow up took 29 weeks before i saw anything on oral, roughly twice what the injection took me 15:40
  • taper_tess — changed my mind on the plain water rule after reading how SNAC works, its not a formality 19:53
  • vik_verifies — quick one the non peptide orals are the interesting part of this channel now, not oral semaglutide 19:55
  • sharps_bin_sid — roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose 19:57
FU

i use it because needles are a genuine problem for me, not because i think its better

SO

follow up took 29 weeks before i saw anything on oral, roughly twice what the injection took me

🤝11🧊4🎉4

one percent is the number people quote and the spread around it is the actual story

my weekly log on oral is noisier than my injectable log ever was, same scales same mornings, ymmv

TW

switched from injectable to oral, lost some of the effect, switched back after 22 months, ill dig out the number

TW

lost 6kg over 9 months on oral, slower than my injectable stretch, i stuck with it anyway

NP

went back to injecting because the morning routine was too fragile around shift work, ymmv

is the absorption variability why the oral doses look so high

tea also does not count, in case anyone was hoping

NP

plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly, for what its worth

oral was easier on my gut than injecting at what felt like a similar effect, which surprised me
the fasting window is the difference between a dose and a very expensive tablet

i keep the tablet by the kettle so i take it before i think about food

big mg small dose

NP

the oral mg number is bigger because almost none of it gets in, thats the entire reason

TT

my oral results were inconsistent week to week and i eventually decided it was me, not the tablet

SC

OASIS ran under the same sort of fasting conditions, thats not the variable between the two

TT

changed my mind on the plain water rule after reading how SNAC works, its not a formality

❤️10
SB

roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose

peptidemeter-summary-h-2814.pdf
2 pages · 216 KB · not retained in the public archive

the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted

i take mine at 6am, is 30 minutes really enough

update on the earlier thing back after 13 months, has anything changed on the oral side