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#oral-glp1 2025-08-14

Thursday23 messages7 participantstimes are UTC
Highlights from this day
  • lisbon_lot — splitting a dose made the absorption problem worse rather than better in my own log 17:03
  • VialBot — Batch lookup B-0329: 2 independent reports on file, earliest 2025-04-07. 17:04
  • spreadsheet_stu — how strict is the 30 minute wait before food for people here 17:37
LM

why is the oral dose in mg so much bigger than the injectable one

big mg small dose

technique probably

the oral disappointed me on the mornings i couldnt manage 30 minutes fasted, which was most of them

LL

lost 39kg over 2 months on oral, slower than my injectable stretch, i stuck with it anyway

plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly

i use it because needles are a genuine problem for me, not because i think its better

PIONEER not OASIS

LM

my oral results were inconsistent week to week and i eventually decided it was me, not the tablet

AA

went back to injecting because the morning routine was too fragile around shift work

LL

splitting a dose made the absorption problem worse rather than better in my own log

janoshik-f-1330.pdf
2 pages · 418 KB · not retained in the public archive
VB

Batch lookup B-0329: 2 independent reports on file, earliest 2025-04-07.

VV

i keep the tablet by the kettle so i take it before i think about food, from memory

LL

coming back to this one percent is the number people quote and the spread around it is the actual story

LL

i said 15 months ago that my oral results were random, they got consistent once i fixed the water
roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose

mine was patchy too

OO

orforglipron is a small molecule rather than a peptide, which is why the fasting conditions differ, anyway

for the archive does SNAC do anything other than get it through the stomach

i take mine at 6am, is 30 minutes really enough

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