did anyone go back to injecting after trying oral
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#oral-glp1 2025-11-07
Friday35 messages7 participantstimes are UTC
Highlights from this day
- electrolyte_eli — right so the oral mg number is bigger because almost none of it gets in, thats the entire reason, from memory 14:33
- electrolyte_eli — the non peptide orals are the interesting part of this channel now, not oral semaglutide 16:19
- surpass_two — oral was easier on my gut than injecting at what felt like a similar effect, which surprised me, for what its worth 17:52
thirty minutes, no cheating
right so the oral mg number is bigger because almost none of it gets in, thats the entire reason, from memory
how strict is the 30 minute wait before food for people here
does the 30 minutes start from swallowing or from the water
did anyone find the oral easier on the gut than the injection
one percent is the number people quote and the spread around it is the actual story
roughly one percent gets absorbed, which is why the tablet strength looks nothing like an injectable dose
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anyone dosing oral because of a needle problem rather than preference
changed my mind on the plain water rule after reading how SNAC works, its not a formality, not advice obviously
set a timer
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OASIS ran under the same sort of fasting conditions, thats not the variable between the two
is the inconsistency people report about the drug or about how they take it
whats the bioavailability actually like, i keep seeing about one percent
i was wrong about the water amount, i was using a sip and it needs a lot more than that
went back to injecting
PIONEER not OASIS
genuine question is orforglipron a peptide at all
the oral disappointed me on the mornings i couldnt manage 30 minutes fasted, which was most of them
i do 6am with water and eat at 7, thats been my routine for 15 months
the non peptide orals are the interesting part of this channel now, not oral semaglutide
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about one percent
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went back to injecting because the morning routine was too fragile around shift work
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ruined my breakfast
does coffee count as plain water, asking for obvious reasons
i said 23 months ago that my oral results were random, they got consistent once i fixed the water, happy to be corrected
is there any point splitting an oral dose
the inconsistency is mostly technique and admitting that took me about a year
coffee is not plain water. i tried it for a month and my results got worse
is the non peptide thing why orforglipron doesnt need the fasting rules
plain water only
oral was easier on my gut than injecting at what felt like a similar effect, which surprised me, for what its worth
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tea also does not count, in case anyone was hoping
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my oral results were inconsistent week to week and i eventually decided it was me, not the tablet
plain water only, about half a glass, then nothing for 30 minutes. i follow it exactly, anyway