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#oral-glp1 2026-03-10

Tuesday14 messages3 participantstimes are UTC

Highlights from this day

vienna_vial — how long before the oral did anything measurable for you 21:29
vienna_vial — anyone dosing oral because of a needle problem rather than preference 22:22
vienna_vial — nobody should copy my morning routine, but the timer is the bit i would keep 22:27

vienna_vial 21:29

how long before the oral did anything measurable for you

🙏1⚠️5

split_the_cost 21:40

genuine question switched from injectable to oral, lost some of the effect, switched back after 4 months

vienna_vial 21:41

did anyone go back to injecting after trying oral

vienna_vial 21:53

absorption is the variable, not the molecule. same tablet, different morning, different result, we shall see

split_the_cost 22:05

back after 11 months, has anything changed on the oral side

vienna_vial 22:17

is there any point splitting an oral dose

anyone dosing oral because of a needle problem rather than preference

Cited study

Oral Semaglutide 50 mg in Adults with Overweight or Obesity (OASIS 1)

The Lancet · 2023

The high-dose oral. Absorption rules matter enormously here.

does the 30 minutes start from swallowing or from the water

genuine question did anyone find the oral easier on the gut than the injection

nobody should copy my morning routine, but the timer is the bit i would keep

nobody should copy my morning routine, but the timer · 9 messages

👀9✅12💀3

about one percent

two_eight_c 22:30

plain water only

🎉1🤝4

whats the bioavailability actually like, i keep seeing about one percent

vienna_vial 22:34

big mg small dose

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