vialroom

#oral-glp1 2026-06-02

Tuesday12 messages4 participantstimes are UTC
Highlights from this day
  • oasis_ola — i keep the tablet by the kettle so i take it before i think about food 12:15
  • VialBot — On this day 4 years ago this channel logged 133 messages. 12:16
  • oasis_ola — the oral disappointed me on the mornings i couldnt manage 30 minutes fasted, which was most of them 12:52
  • ten_of_ten — the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted, anyway 14:10
  • identity_shift — whats the bioavailability actually like, i keep seeing about one percent 16:06
OO

i keep the tablet by the kettle so i take it before i think about food

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VB

On this day 4 years ago this channel logged 133 messages.

OO

the oral disappointed me on the mornings i couldnt manage 30 minutes fasted, which was most of them

TO

anyone switched from injectable to oral and kept the same effect

OO

went back to injecting because the morning routine was too fragile around shift work

TO

is the non peptide thing why orforglipron doesnt need the fasting rules

TO

the 30 minutes starts when you swallow it, and i set a timer because i cannot be trusted, anyway

TO

did anyone get consistent results on the oral or is it always patchy

IS

whats the bioavailability actually like, i keep seeing about one percent

Cited study
Oral Semaglutide 50 mg in Adults with Overweight or Obesity (OASIS 1)
The Lancet · 2023
The high-dose oral. Absorption rules matter enormously here.
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OO

quick one back after 10 months, has anything changed on the oral side