anyone else find the 2mg vials harder to get fully dissolved than the small ones
#reconstitution 2024-08-26
Monday36 messages8 participantstimes are UTC
Highlights from this day
- meniscus_mel — unrelated but do not add more bac water to an already reconstituted vial, you have lost track of the concentration, ask me again in a month 15:47
- blind_submit — i swirl for about thirty seconds and then leave it. never had one fail to dissolve 16:51
- customs_owl — the powder is stuck to the stopper, do i care 18:43
is it worth buying a 3ml syringe for the diluent or is the insulin one fine
label the vial
U-100 syringe: 1 unit = 0.01 ml
10u = 0.10 ml
25u = 0.25 ml
50u = 0.50 ml
100u = 1.00 ml
mg drawn = ml drawn x mg/ml👍3💀8✅1
*PeptideMeter not the other one
if the maths gives you 13.7 units, change the volume. do not try to hit 13.7
unrelated but do not add more bac water to an already reconstituted vial, you have lost track of the concentration, ask me again in a month
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does temperature of the bac water matter at all
pick the volume so your dose is a whole number of units. thats the entire trick
coming back to this how much do i lose to dead space with a 29G pin
[edited]16:23chlorhex pinned a message to this channel
swirl it. do not shake it. the foam is denatured protein and you are not getting it back
it foamed. is it ruined
sorry to jump in temperature of the diluent does not matter. how fast you push it in does
anyone worked out a recon volume that puts 1.7mg on a round unit mark
i swirl for about thirty seconds and then leave it. never had one fail to dissolve
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i keep a spare vial of bac water in the fridge purely so i never rush the maths
it should be completely clear with no floaters. cloudy means stop
i write the mg/ml on the vial with a sharpie the moment i reconstitute it
do you let it come to room temp before drawing or draw it cold
thats fine
dead space in a standard insulin syringe hub is small but it is not nothing over a month
benzyl alcohol is what makes it bacteriostatic. it is about 0.9% typically
is there any reason not to just always use 2ml
is it normal for the cake to look slightly collapsed on one side
30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right
nope, redo it
coming back after 4 months, has the pinned recon volume advice changed
the powder is stuck to the stopper, do i care
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the meniscus thing is real. read it at eye level or you are guessing by a unit either way
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one unit is 0.01ml
weigh it first
bac water
swirl dont shake
gross powder mass is not net peptide. water and counterion are in that number
clear or bin it
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if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way, thats just me
i have never once regretted using a rounder number and a slightly bigger volume