sanity check my maths before i pin myself with something stupid
#reconstitution 2025-12-15
Monday51 messages11 participantstimes are UTC
Highlights from this day
- slow.taper — anyone else find the 15mg vials harder to get fully dissolved than the small ones took me a year to stop over-diluting. the measurement error at 4 units is worse than… 20:09
- retention_time — temperature of the diluent does not matter. how fast you push it in does 20:58
- declared_value — i swirl for about thirty seconds and then leave it. never had one fail to dissolve 21:25
anyone worked out a recon volume that puts 1.7mg on a round unit mark
i was wrong about this last year: it is fine to draw cold, it just stings more going in
one unit is 0.01ml. 100 units is 1ml. everything else in this channel follows from that
is a slightly cloudy solution ever ok or is that always a bin it
10mg in 1ml is 10mg/ml, so 2.5mg is 25 units. thats the one i use
if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way
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anyone else find the 15mg vials harder to get fully dissolved than the small ones
took me a year to stop over-diluting. the measurement error at 4 units is worse than the convenience
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On this day 3 years ago this channel logged 129 messages.
is it worth buying a 3ml syringe for the diluent or is the insulin one fine
genuine question 10mg in 2ml is 5mg/ml. so 0.5mg is 0.1ml which is 10 units on a u100
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benzyl alcohol is what makes it bacteriostatic. it is about 0.9% typically
i have never once regretted using a rounder number and a slightly bigger volume, ill dig out the number
the meniscus thing is real. read it at eye level or you are guessing by a unit either way
dead space
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do not add more bac water to an already reconstituted vial, you have lost track of the concentration
20mg in 2ml is 10mg/ml. 1mg is 10 units, 2mg is 20 units, easy
it should be completely clear with no floaters. cloudy means stop
yep 10 units
foam is bad
i use bac water even for a single-use vial because it stings less, which is not the reason it exists
temperature of the diluent does not matter. how fast you push it in does
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clear or bin it
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label the vial
update from 23 months ago: switched to a single concentration and have not miscalculated since
[edited]Channel stats, last 30 days: 138 messages from 20 members.
if you cannot read the mark confidently, your volume is too small. redo it at a lower concentration
the vacuum will pull it in. let it. fighting it is how you get a face full of aerosol
ok so bacteriostatic water for anything multi-use. sterile water has no preservative in it at all, not advice obviously
took me a year to stop over-diluting. the measurement error at 4 units is worse than the convenience, for what its worth
i swirl for about thirty seconds and then leave it. never had one fail to dissolve
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do you let it come to room temp before drawing or draw it cold
write the date on
swirl dont shake
i write the mg/ml on the vial with a sharpie the moment i reconstitute it
unrelated but what do you do with the last 15 units when you cant draw them cleanly
i keep a spare vial of bac water in the fridge purely so i never rush the maths, not advice obviously
aim the diluent at the glass wall, not at the powder. it goes in gentler
thats fine
how do you all measure a half unit, or do you just not
swirl it. do not shake it. the foam is denatured protein and you are not getting it back
nope, redo it
the powder is stuck to the stopper, do i care
*VendorInvestigate not the other one
anyone got a photo of what a properly dissolved vial looks like
lyophilised powder is far more robust than people think. it is the solution that is fragile
gross powder mass is not net peptide. water and counterion are in that number
a 3ml syringe for the diluent and a u100 for the dose is the setup most people here end up with, n of 1 obviously
label the date too. you will not remember which vial is which by week 5
while im here how long after reconstituting before its actually dissolved
dead space in a standard insulin syringe hub is small but it is not nothing over a month
[edited]a slightly collapsed cake is cosmetic. a puddle in the bottom is not
temperature of the diluent does not matter. how fast you push it in does