how do you all measure a half unit, or do you just not
#reconstitution 2026-03-25
Wednesday45 messages9 participantstimes are UTC
Highlights from this day
- vialkeeper — i was wrong about this last year: it is fine to draw cold, it just stings more going in 07:22
- birch_bloods — if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space 09:44
- iris_imports — i use bac water even for a single-use vial because it stings less, which is not the reason it exists 10:19
- birch_bloods — do i swirl for a specific length of time or just until its clear 11:03
15mg in 3ml is 5mg/ml. same numbers as 10 in 2, just more of it
follow up label the date too. you will not remember which vial is which by week 5
update from 1 months ago: switched to a single concentration and have not miscalculated since
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does benzyl alcohol matter if im finishing the vial in one go
can i add more bac water later to a vial ive already reconstituted
U-100 syringe: 1 unit = 0.01 ml
10u = 0.10 ml
25u = 0.25 ml
50u = 0.50 ml
100u = 1.00 ml
mg drawn = ml drawn x mg/mlif the powder is on the stopper, tap it down before you add anything. it will still dissolve either way
i was wrong about this last year: it is fine to draw cold, it just stings more going in
10mg vial
+ 1.0ml -> 10.0 mg/ml 0.5mg = 5u 1mg = 10u
+ 2.0ml -> 5.0 mg/ml 0.5mg = 10u 1mg = 20u
+ 2.5ml -> 4.0 mg/ml 0.5mg = 12.5u (dont)
+ 5.0ml -> 2.0 mg/ml 0.5mg = 25u 1mg = 50u💀1🔥1
read it at eye level
if you cannot read the mark confidently, your volume is too small. redo it at a lower concentration
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i swirl for about thirty seconds and then leave it. never had one fail to dissolve
weighing the vial before you reconstitute is the only way to catch an underfill
you can absolutely just always use 2ml, and honestly most of us should
i have never once regretted using a rounder number and a slightly bigger volume
a slightly collapsed cake is cosmetic. a puddle in the bottom is not
10mg vial
+ 1.0ml -> 10.0 mg/ml 0.5mg = 5u 1mg = 10u
+ 2.0ml -> 5.0 mg/ml 0.5mg = 10u 1mg = 20u
+ 2.5ml -> 4.0 mg/ml 0.5mg = 12.5u (dont)
+ 5.0ml -> 2.0 mg/ml 0.5mg = 25u 1mg = 50udead space
dead space in a standard insulin syringe hub is small but it is not nothing over a month
update on the earlier thing took me a year to stop over-diluting. the measurement error at 4 units is worse than the convenience
swirl dont shake
is a slightly cloudy solution ever ok or is that always a bin it
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one unit is 0.01ml. 100 units is 1ml. everything else in this channel follows from that
for the archive my rule is one concentration for everything so i never have to think about it at 7am
thats 5mg/ml
i keep a spare vial of bac water in the fridge purely so i never rush the maths
check your maths
bac water
is there any reason not to just always use 2ml
nope, redo it
the jewellery scale is a good habit but calibrate it, they drift badly
if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space
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swirl it. do not shake it. the foam is denatured protein and you are not getting it back
yep 10 units
i use bac water even for a single-use vial because it stings less, which is not the reason it exists
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*Medutest not the other one
why does everyone say 2ml specifically and not 1ml
do i swirl for a specific length of time or just until its clear
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whats the smallest volume you would trust yourself to measure on a u100
not sterile water
clear or bin it
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the vacuum will pull it in. let it. fighting it is how you get a face full of aerosol
temperature of the diluent does not matter. how fast you push it in does
foam is bad
if the maths gives you 13.7 units, change the volume. do not try to hit 13.7, n of 1 obviously
aim the diluent at the glass wall, not at the powder. it goes in gentler
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bacteriostatic water for anything multi-use. sterile water has no preservative in it at all