vialroom

#reconstitution 2026-04-16

Thursday34 messages5 participantstimes are UTC
Highlights from this day
  • cold_chain_cmdr — update from 12 months ago: switched to a single concentration and have not miscalculated since, from memory 19:58
  • meniscus_mel — i keep a spare vial of bac water in the fridge purely so i never rush the maths 20:21
  • nhs_pathway_nell — slightly off topic but lyophilised powder is far more robust than people think. it is the solution that is fragile 20:52

the jewellery scale is a good habit but calibrate it, they drift badly

MM

nobody here should be telling you a dose. we can check your arithmetic, thats a different thing

NP

30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right

i have never once regretted using a rounder number and a slightly bigger volume, not advice obviously

coming back to this is it normal for the cake to look slightly collapsed on one side

do you draw up with the same pin you inject with

i write the mg/ml on the vial with a sharpie the moment i reconstitute it, thats one data point

MM

pick the volume so your dose is a whole number of units. thats the entire trick

[edited]
SB

unrelated but i use bac water even for a single-use vial because it stings less, which is not the reason it exists

SB

weighing the vial before you reconstitute is the only way to catch an underfill, ask me again in a month

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do i swirl for a specific length of time or just until its clear

CC

update from 12 months ago: switched to a single concentration and have not miscalculated since, from memory

15📈1

i was wrong about this last year: it is fine to draw cold, it just stings more going in

MM

i keep a spare vial of bac water in the fridge purely so i never rush the maths

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SB

coming back after 19 months, has the pinned recon volume advice changed

label the vial

[edited]

*Medutest not the other one

NP

slightly off topic but lyophilised powder is far more robust than people think. it is the solution that is fragile

[edited]
⚠️15
RR

unrelated but anyone worked out a recon volume that puts 5mg on a round unit mark
dead space in a standard insulin syringe hub is small but it is not nothing over a month

CC

dead space in a standard insulin syringe hub is small but it is not nothing over a month

*week 34 not week 4

the powder is stuck to the stopper, do i care

9
SB

if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way

RR

if you draw up with a bigger pin and inject with a fresh one you lose a bit more to dead space