slightly off topic but dead space in a standard insulin syringe hub is small but it is not nothing over a month
#reconstitution 2026-06-18
Thursday50 messages11 participantstimes are UTC
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for the archive is the meniscus reading actually a real source of error or am i overthinking
dead space
temperature of the diluent does not matter. how fast you push it in does
i swirl for about thirty seconds and then leave it. never had one fail to dissolve
ok so bac water or sterile water for something im going into weekly for 4 weeks
i was wrong about this last year: it is fine to draw cold, it just stings more going in, we shall see
does temperature of the bac water matter at all
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not sterile water
unrelated but is there any reason not to just always use 2ml
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i use bac water even for a single-use vial because it stings less, which is not the reason it exists
my rule is one concentration for everything so i never have to think about it at 7am
weigh it first
20mg in 2ml is 10mg/ml. 1mg is 10 units, 2mg is 20 units, easy, thats one data point
the vacuum will pull it in. let it. fighting it is how you get a face full of aerosol
Digest for the week of 2026-03-31 has been published.
is it normal for the cake to look slightly collapsed on one side
coming back after 17 months, has the pinned recon volume advice changed
my vial pulled the water in on its own, is that the vacuum or did i do something
does it matter if i inject the bac water straight at the powder
5mg in 2ml gives 2.5mg/ml, 0.25mg is 10 units. good for a starting dose
label the date too. you will not remember which vial is which by week 20
bacteriostatic water for anything multi-use. sterile water has no preservative in it at all
if the powder is on the stopper, tap it down before you add anything. it will still dissolve either way, still working it out
the powder is stuck to the stopper, do i care
Purity check: no report on file for lot G-0641. Nothing logged either way.
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is it worth buying a 3ml syringe for the diluent or is the insulin one fine
5mg in 2ml gives 2.5mg/ml, 0.25mg is 10 units. good for a starting dose
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sanity check my maths before i pin myself with something stupid
foam is bad
if the maths gives you 13.7 units, change the volume. do not try to hit 13.7
update from 22 months ago: switched to a single concentration and have not miscalculated since
On this day 7 years ago this channel logged 26 messages.
you can absolutely just always use 2ml, and honestly most of us should
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for the archive weighing the vial before you reconstitute is the only way to catch an underfill
bac water
sorry to jump in a slightly collapsed cake is cosmetic. a puddle in the bottom is not
genuine question 30mg in 3ml is 10mg/ml, so 5mg is 50 units. half the barrel, feels like a lot but its right
how much do i lose to dead space with a 31G pin
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update on the earlier thing anyone else find the 5mg vials harder to get fully dissolved than the small ones
*VendorInvestigate not the other one
it should be completely clear with no floaters. cloudy means stop
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swirl dont shake
i have never once regretted using a rounder number and a slightly bigger volume
yep 10 units
read it at eye level
too dilute imo
thats the vacuum
pick the volume so your dose is a whole number of units. thats the entire trick, take that with a pinch of salt
thats 5mg/ml