the honest position is this has less human evidence behind it than anything else discussed here
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#retatrutide 2024-07-18
Thursday31 messages7 participantstimes are UTC
Highlights from this day
- chlorhex — the honest position is this has less human evidence behind it than anything else discussed here 10:04
- two_four_ceiling — stepping in 10 increments instead of doubling is the only thing i would change if i started again, ask me again in a month 11:25
- chlorhex — the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me, anyway i was wrong to call the heart rate a non issue last year,… 15:04
appetite suppression at 1.7 was stronger than my tirzepatide experience at a comparable point
the heart rate thing is real enough that i mention it whenever someone asks about starting
triple agonist meaning GLP-1, GIP and glucagon, have i got that right
anyone stayed at 12 for months rather than climbing
i log resting heart rate every morning because of this and its the one number i actually watch
logging rhr daily
held mine ages
blood pressure stayed flat for me while heart rate moved, which i didnt expect
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
whats the half life like, is it weekly the same way
stopped for 17 months and restarted at half my old dose, the ramp was easier second time
i said 9 months ago that my heart rate had settled and it has stayed settled since
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low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
anyone reconstituting 30 vials to 4 so the steps come out smaller
stepping in 10 increments instead of doubling is the only thing i would change if i started again, ask me again in a month
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
low and slow
people insist on small steps because the side effects arrive faster than on the other two
research use only
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energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, from memory
anyone tracking blood pressure alongside the heart rate
cant feel it honestly
whats a sensible starting point, im seeing everything from 0.5 to 2
settled by month three
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps, from memory
phase 2 only
reta_resting_hrphase 2 doses are published and theyre not far off what people here run, coincidence…
held at 1 for 25 months and it never plateaued for me, which i cant explain
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me, anyway
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
smaller steps here