vialroom

#retatrutide 2024-07-19

Friday29 messages6 participantstimes are UTC
Highlights from this day
  • two_four_ceiling — held at 2.4 for 18 months and it never plateaued for me, which i cant explain, we shall see 13:13
  • surpass_two — anyone compared their PeptideMeter purity across two different QST lots 13:50
  • two_four_ceiling — energy expenditure isnt something i could feel, though my sleep tracker disagreed with me 15:38
  • gradient_greg — anyone logging resting heart rate on this 17:54
  • surpass_two — triple agonist meaning GLP-1, GIP and glucagon, have i got that right 18:06
TF

sat at 12 for 3 months rather than climbing and it kept working, so i never went up

TF

held at 2.4 for 18 months and it never plateaued for me, which i cant explain, we shall see

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ST

triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history

ST

anyone compared their PeptideMeter purity across two different QST lots

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.
TF

research use only

fridge-temps.csv
145 rows · not retained in the public archive
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TF

lost 37kg over 17 months at doses well under what the trials used, i have it written down somewhere

TF

the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial

energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

📈7

appetite suppression at 0.25 was stronger than my tirzepatide experience at a comparable point, ymmv

TF

stepping in 1 increments instead of doubling is the only thing i would change if i started again

im at 2 and the appetite effect is stronger than i expected, normal

ST

while im here does the energy expenditure claim show up as anything you can feel

ST

my resting rate went up 4 bpm in the first month and came back most of the way by month 8

GG

low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

😂3
HH

i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps

HH

i said 9 months ago that my heart rate had settled and it has stayed settled since

HH

genuine question Janoshik came back 97.4 on one lot and 99 on the next from the same SGN, both fine

ST

is the glucagon arm what people mean by the energy expenditure thing

ST

triple agonist meaning GLP-1, GIP and glucagon, have i got that right

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