stopped for 25 months and restarted at half my old dose, the ramp was easier second time
#retatrutide 2024-11-03
Sunday43 messages10 participantstimes are UTC
Highlights from this day
- snac_and_water — reconstituted the 5 vial to 4mg/ml specifically so i could take 12 without measuring crumbs 19:52
- truncation_tru — lost 4kg over 23 months at doses well under what the trials used, not advice obviously 21:22
- relabel_watch — is the phase 2 dosing anywhere near what people here run 22:01
reconstituted the 5 vial to 4mg/ml specifically so i could take 12 without measuring crumbs
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cant feel it honestly
whats the half life like, is it weekly the same way
nobody should read my log as a plan, im recording what i did and thats all it is, ill dig out the number
logging rhr daily
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
the honest position is this has less human evidence behind it than anything else discussed here
does the energy expenditure claim show up as anything you can feel
stepping in 2.5 increments instead of doubling is the only thing i would change if i started again
triple agonist yeah
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
came off at 19 weeks because my resting rate stayed elevated and i didnt like it
how slow is low and slow here, four weeks a step or longer
glucagon is the new bit
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people insist on small steps because the side effects arrive faster than on the other two
research use only
the heart rate thing is real enough that i mention it whenever someone asks about starting
did anyone come off because of the heart rate
watching my heart rate
follow up low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
smaller steps here
coming back to this i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
lost 4kg over 23 months at doses well under what the trials used, not advice obviously
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settled by month three
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coming back to this research use only is on every vial and i treat it as exactly that, nobody here is prescribing
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no long term data
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Inter-lab diff for lot E-2205: 98.6% vs 99.4%. Within expected range.
whats a sensible starting point, im seeing everything from 0.5 to 2
is the phase 2 dosing anywhere near what people here run
held mine ages
TRIUMPH is phase 3
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)mine went up too
the half life supports weekly dosing and thats what ive done from the start
quick one blood pressure stayed flat for me while heart rate moved, which i didnt expect
medutest-report-f-1330.pdf
3 pages · 896 KB · not retained in the public archive
why does everyone insist on smaller steps here than on the other two
the purity spread across lots worries me more than the molecule does
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, your mileage will differ
GI was about the same as tirzepatide for me, the difference was how fast it arrived
phase 2 only
stepping in 5 increments instead of doubling is the only thing i would change if i started again
my resting rate went up 2 bpm in the first month and came back most of the way by month 26
triple agonist meaning GLP-1, GIP and glucagon, have i got that right
sat at 5 for 8 months rather than climbing and it kept working, so i never went up