vialroom

#retatrutide 2024-11-04

Monday29 messages6 participantstimes are UTC
Highlights from this day
  • a1c_lag — quick one i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind 02:39
  • no_appetite_nia — is TRIUMPH the phase 3 programme 02:40
  • no_appetite_nia — does the energy expenditure claim show up as anything you can feel 03:37
  • reship_rita — the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial 04:05
  • reship_rita — VendorInvestigate came back 98.1 on one lot and 99.2 on the next from the same BCH, both fine 04:06

whats the half life like, is it weekly the same way

energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

RR

why does everyone insist on smaller steps here than on the other two

RR

held at 2 for 10 months and it never plateaued for me, which i cant explain

did the phase 2 plateau or was it still moving at the end

A1

TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, i could be wrong

unrelated but the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me

quick one i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind

🧊18
NA

is TRIUMPH the phase 3 programme

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)
RR

logging rhr daily

baseline  58
wk 2      61
wk 4      64
wk 6      67
wk 8      66
wk 10     65   (held dose from wk 7)
NP

i log resting heart rate every morning because of this and its the one number i actually watch

RR

right so i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps

NA

does the energy expenditure claim show up as anything you can feel

🔥13❤️14📈1
RR

the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial

lot-log.csv
184 rows · not retained in the public archive

VendorInvestigate came back 98.1 on one lot and 99.2 on the next from the same BCH, both fine

🤝3🙏5😂11
NA

phase 2 was still trending at the end which is why the phase 3 readout matters more than usual

*Medutest not the other one

back after 8 months, has anything actually been published since
my resting rate went up 9 bpm in the first month and came back most of the way by month 15

[edited]

*Janoshik not the other one

DD

did the phase 2 result actually come in higher than the tirzepatide numbers

the honest position is this has less human evidence behind it than anything else discussed here

right so how long before people saw the first change at 7.5

RR

is there any long term safety data at all or is it phase 2 and hope

watching my heart rate