vialroom

#retatrutide 2025-04-03

Thursday34 messages8 participantstimes are UTC
Highlights from this day
  • VialBot — On this day 6 years ago this channel logged 97 messages. 19:32
  • VialBot — Recon calculator: 30mg in 3ml = 4mg/ml. 21:30
  • see_a_clinician — GI was about the same as tirzepatide for me, the difference was how fast it arrived 21:33
NP

the honest position is this has less human evidence behind it than anything else discussed here

NP

sorry to jump in stopped for 22 months and restarted at half my old dose, the ramp was easier second time, for what its worth

LL

the heart rate thing is real enough that i mention it whenever someone asks about starting

VB

On this day 6 years ago this channel logged 97 messages.

👍11🤝9
NP

energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

GG

low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom

phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
research use only is on every vial and i treat it as exactly that, nobody here is prescribing

SA

buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely

back after 1 months, has anything actually been published since

🧊10
NP

my resting rate went up 6 bpm in the first month and came back most of the way by month 23

IS

lost 30kg over 9 months at doses well under what the trials used, n of 1 obviously

NP

sat at 2 for 8 months rather than climbing and it kept working, so i never went up

Recon calculator: 30mg in 3ml = 4mg/ml.

👀47

triple agonist meaning GLP-1, GIP and glucagon, have i got that right

does the glucagon arm explain the heart rate or is that unrelated

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.

is TRIUMPH the phase 3 programme

SA

blood pressure stayed flat for me while heart rate moved, which i didnt expect