anyone gone above 2.4 and what changed
#retatrutide 2025-04-05
Saturday51 messages9 participantstimes are UTC
Highlights from this day
- pin29g — reconstituted the 15 vial to 2.5mg/ml specifically so i could take 7.5 without measuring crumbs 20:05
- area_percent — how slow is low and slow here, four weeks a step or longer 20:33
- area_percent — research use only is on every vial and i treat it as exactly that, nobody here is prescribing 21:38
- reta_resting_hr — came off at 32 weeks because my resting rate stayed elevated and i didnt like it 22:10
is TRIUMPH the phase 3 programme
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
reconstituted the 15 vial to 2.5mg/ml specifically so i could take 7.5 without measuring crumbs
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smaller steps here
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nobody should read my log as a plan, im recording what i did and thats all it is
ok so my resting rate went up 7 bpm in the first month and came back most of the way by month 19, ill dig out the number
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whats a sensible starting point, im seeing everything from 0.5 to 2
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why does everyone insist on smaller steps here than on the other two
stepping in 7.5 increments instead of doubling is the only thing i would change if i started again
whats the half life like, is it weekly the same way
for the archive held at 2 for 5 months and it never plateaued for me, which i cant explain
logging rhr daily
sat at 12 for 2 months rather than climbing and it kept working, so i never went up
is the glucagon arm what people mean by the energy expenditure thing
how slow is low and slow here, four weeks a step or longer
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watching my heart rate
unrelated but how long before people saw the first change at 2
low and slow
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
i log resting heart rate every morning because of this and its the one number i actually watch
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follow up my resting heart rate is up about 5 bpm, did that settle for anyone
for the archive energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
anyone compared their Medutest purity across two different ERP lots
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
people insist on small steps because the side effects arrive faster than on the other two
the purity spread across lots worries me more than the molecule does
did the phase 2 plateau or was it still moving at the end
Reminder set. I will post here in 4 days.
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is there any long term safety data at all or is it phase 2 and hope
phase 2 only
follow up the honest position is this has less human evidence behind it than anything else discussed here
did the phase 2 result actually come in higher than the tirzepatide numbers
anyone tracking blood pressure alongside the heart rate
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research use only is on every vial and i treat it as exactly that, nobody here is prescribing
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while im here i said 8 months ago that my heart rate had settled and it has stayed settled since
21:56quiet.hours pinned a message to this channel
triple agonist meaning GLP-1, GIP and glucagon, have i got that right
blood pressure stayed flat for me while heart rate moved, which i didnt expect
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
sat at 5 for 9 months rather than climbing and it kept working, so i never went up
came off at 32 weeks because my resting rate stayed elevated and i didnt like it
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anyone logging resting heart rate on this
Medutest came back 96.8 on one lot and 99.4 on the next from the same CPC, both fine
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*VendorInvestigate not the other one
follow up anyone reconstituting 5 vials to 8 so the steps come out smaller
stopped for 17 months and restarted at half my old dose, the ramp was easier second time
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mine went up too
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps, take that with a pinch of salt
is the GI worse than tirzepatide or about the same
im at 0.25 and the appetite effect is stronger than i expected, normal