whats the half life like, is it weekly the same way
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#retatrutide 2025-09-28
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Highlights from this day
- lot_number_lou — whats the half life like, is it weekly the same way 16:47
- bea_reconstitutes — anyone logging resting heart rate on this 17:42
- mcg_not_mg — unrelated but lost 47kg over 13 months at doses well under what the trials used 17:49
- nhs_pathway_nell — anyone compared their PeptideMeter purity across two different FGP lots 19:54
- knees_first — im at 2.4 and the appetite effect is stronger than i expected, normal i log resting heart rate every morning because of this and its the one number i actually watch 21:03
does the glucagon arm explain the heart rate or is that unrelated
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me, for what its worth
TRIUMPH is phase 3
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the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
why does everyone insist on smaller steps here than on the other two
came off at 30 weeks because my resting rate stayed elevated and i didnt like it, thats just me
genuine question appetite suppression at 1 was stronger than my tirzepatide experience at a comparable point
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
stepping in 5 increments instead of doubling is the only thing i would change if i started again
stopped for 13 months and restarted at half my old dose, the ramp was easier second time
coming back to this i said 9 months ago that my heart rate had settled and it has stayed settled since
how do people square the research use only framing with logging their own use
anyone logging resting heart rate on this
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settled by month three
held mine ages
unrelated but lost 47kg over 13 months at doses well under what the trials used
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sat at 1 for 8 months rather than climbing and it kept working, so i never went up
no idea whether the heart rate settles for everyone, mine did and one log isnt data
low and slow
the purity spread across lots worries me more than the molecule does
research use only is on every vial and i treat it as exactly that, nobody here is prescribing, i think
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
smaller steps here
the half life supports weekly dosing and thats what ive done from the start
mine went up too
the heart rate thing is real enough that i mention it whenever someone asks about starting
is the phase 2 dosing anywhere near what people here run
anyone compared their PeptideMeter purity across two different FGP lots
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
is there any long term safety data at all or is it phase 2 and hope
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists, take that with a pinch of salt
no long term data
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cant feel it honestly
anyone gone above 15 and what changed
ok so blood pressure stayed flat for me while heart rate moved, which i didnt expect, take that with a pinch of salt
logging rhr daily
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nobody should read my log as a plan, im recording what i did and thats all it is
*that should say weekly
im at 2.4 and the appetite effect is stronger than i expected, normal
i log resting heart rate every morning because of this and its the one number i actually watch
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
glucagon is the new bit