logging rhr daily
#retatrutide 2026-01-10
- mhra_unlicensed — the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial, not advice obviously 09:48
- VialBot — Verification log updated: FGP — evidence added, status unchanged. 10:40
- first_and_last_four — my resting rate went up 6 bpm in the first month and came back most of the way by month 2 stepping in 2.4 increments instead of doubling is the only thing i would… 12:01
TRIUMPH is phase 3
lost 4kg over 25 months at doses well under what the trials used
held at 2 for 25 months and it never plateaued for me, which i cant explain
came off at 21 weeks because my resting rate stayed elevated and i didnt like it
did the phase 2 plateau or was it still moving at the end
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial, not advice obviously
anyone compared their Medutest purity across two different SWB lots
no idea whether the heart rate settles for everyone, mine did and one log isnt data
i log resting heart rate every morning because of this and its the one number i actually watch
no long term data
anyone reconstituting 5 vials to 4 so the steps come out smaller
is TRIUMPH the phase 3 programme
blood pressure stayed flat for me while heart rate moved, which i didnt expect
glucagon is the new bit
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps
im at 0.25 and the appetite effect is stronger than i expected, normal
is the phase 2 dosing anywhere near what people here run
held at 5 for 3 months and it never plateaued for me, which i cant explain
how long before people saw the first change at 2
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
research use only is on every vial and i treat it as exactly that, nobody here is prescribing
whats a sensible starting point, im seeing everything from 0.5 to 2
the half life supports weekly dosing and thats what ive done from the start
Verification log updated: FGP — evidence added, status unchanged.
low and slow
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)held mine ages
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
triple agonist yeah
sat at 10 for 9 months rather than climbing and it kept working, so i never went up
did the phase 2 result actually come in higher than the tirzepatide numbers
is the GI worse than tirzepatide or about the same
my resting heart rate is up about 4 bpm, did that settle for anyone
smaller steps here
my resting rate went up 6 bpm in the first month and came back most of the way by month 2
stepping in 2.4 increments instead of doubling is the only thing i would change if i started again
triple agonist meaning GLP-1, GIP and glucagon, have i got that right
*that should say weekly
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
update on the earlier thing is the glucagon arm what people mean by the energy expenditure thing
mine went up too
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)anyone logging resting heart rate on this
settled by month three
how do people square the research use only framing with logging their own use
*PeptideMeter not the other one
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
watching my heart rate
did anyone come off because of the heart rate
the heart rate thing is real enough that i mention it whenever someone asks about starting, still working it out
phase 2 only
cant feel it honestly
research use only
how slow is low and slow here, four weeks a step or longer
Medutest came back 99.4 on one lot and 98.1 on the next from the same HJ, both fine, i could be wrong
does the glucagon arm explain the heart rate or is that unrelated
appetite suppression at 5 was stronger than my tirzepatide experience at a comparable point
people insist on small steps because the side effects arrive faster than on the other two
why does everyone insist on smaller steps here than on the other two
GI was about the same as tirzepatide for me, the difference was how fast it arrived
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
Batch lookup A-2418: 6 independent reports on file, earliest 2025-12-11.
reconstituted the 20 vial to 8mg/ml specifically so i could take 0.5 without measuring crumbs
back after 22 months, has anything actually been published since
the honest position is this has less human evidence behind it than anything else discussed here
Reminder for lisbon_lot: dose day is today. Set 8 days ago.
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
stopped for 20 months and restarted at half my old dose, the ramp was easier second time
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists