vialroom

#retatrutide 2026-01-25

Sunday19 messages7 participantstimes are UTC
Highlights from this day
  • triumph_watch — phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan 14:56
  • triumph_watch — anyone compared their Janoshik purity across two different WWB lots 15:49
  • back_from_away — back after 18 months, has anything actually been published since 16:29
  • oasis_ola — people insist on small steps because the side effects arrive faster than on the other two the purity spread across lots worries me more than the molecule does 16:49
KM

why does everyone insist on smaller steps here than on the other two

TW

phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.
OO

buying this is a completely different risk conversation from the licensed compounds and that gets said too rarely

[edited]
TW

phase 2 was still trending at the end which is why the phase 3 readout matters more than usual

OO

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists

VB

Testing queue: 9 submissions open, 75 awaiting dispatch.

BF

back after 18 months, has anything actually been published since

🙏12⚠️11

unrelated but the honest position is this has less human evidence behind it than anything else discussed here
the purity spread across lots worries me more than the molecule does

GI was about the same as tirzepatide for me, the difference was how fast it arrived
people insist on small steps because the side effects arrive faster than on the other two

OO

people insist on small steps because the side effects arrive faster than on the other two
the purity spread across lots worries me more than the molecule does

👀1🔥14

triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history, ymmv

is the GI worse than tirzepatide or about the same

💀2
TW

sat at 0.25 for 8 months rather than climbing and it kept working, so i never went up

FA

the purity spread across lots worries me more than the molecule does