whats the half life like, is it weekly the same way
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#retatrutide 2026-02-05
Thursday42 messages11 participantstimes are UTC
Highlights from this day
- triumph_watch — phase 2 was still trending at the end which is why the phase 3 readout matters more than usual 09:32
- egfr_ed — back after 11 months, has anything actually been published since 11:58
- triumph_watch — the heart rate thing is real enough that i mention it whenever someone asks about starting 12:43
how slow is low and slow here, four weeks a step or longer
why does everyone insist on smaller steps here than on the other two
anyone compared their VendorInvestigate purity across two different GGPeps lots
logging rhr daily
blood pressure stayed flat for me while heart rate moved, which i didnt expect, ask me again in a month
phase 2 only
Assay note: QSC lot E-2205 reported at 96.8% of label content.
is the GI worse than tirzepatide or about the same
did the phase 2 plateau or was it still moving at the end
*Medutest not the other one
the half life supports weekly dosing and thats what ive done from the start
quick one anyone tracking blood pressure alongside the heart rate
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)does the energy expenditure claim show up as anything you can feel
janoshik-b-0114.pdf
2 pages · 828 KB · not retained in the public archive
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)lost 8kg over 26 months at doses well under what the trials used, thats just me
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the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial
glucagon is the new bit
*PeptideMeter not the other one
GI was about the same as tirzepatide for me, the difference was how fast it arrived
im at 7.5 and the appetite effect is stronger than i expected, normal
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
how do people square the research use only framing with logging their own use
stepping in 0.25 increments instead of doubling is the only thing i would change if i started again
watching my heart rate
[edited]did anyone come off because of the heart rate
stopped for 13 months and restarted at half my old dose, the ramp was easier second time
sat at 5 for 7 months rather than climbing and it kept working, so i never went up
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
anyone reconstituting 2 vials to 2 so the steps come out smaller
nobody should read my log as a plan, im recording what i did and thats all it is
my resting rate went up 6 bpm in the first month and came back most of the way by month 7
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
held mine ages
back after 11 months, has anything actually been published since
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coming back to this VendorInvestigate came back 98.1 on one lot and 99.2 on the next from the same WWB, both fine
appetite suppression at 0.5 was stronger than my tirzepatide experience at a comparable point
the honest position is this has less human evidence behind it than anything else discussed here
is the phase 2 dosing anywhere near what people here run
the purity spread across lots worries me more than the molecule does
the heart rate thing is real enough that i mention it whenever someone asks about starting
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)settled by month three
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)💀4🧊1🙏2