anyone stayed at 1.7 for months rather than climbing
#retatrutide 2026-02-10
Tuesday49 messages8 participantstimes are UTC
Highlights from this day
- quiet_head_qi — the honest position is this has less human evidence behind it than anything else discussed here 21:15
- nhs_pathway_nell — how long before people saw the first change at 1 21:43
- vale_vials — is TRIUMPH the phase 3 programme 21:52
- group_buy_gwen — while im here no idea whether the heart rate settles for everyone, mine did and one log isnt data, ask me again in a month 22:28
- group_buy_gwen — did the phase 2 result actually come in higher than the tirzepatide numbers 22:47
anyone compared their PeptideMeter purity across two different CPC lots
the honest position is this has less human evidence behind it than anything else discussed here
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phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
*VendorInvestigate not the other one
triple agonist meaning GLP-1, GIP and glucagon, have i got that right
triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
came off at 27 weeks because my resting rate stayed elevated and i didnt like it
Medutest came back 99 on one lot and 98.6 on the next from the same SWB, both fine
lost 36kg over 21 months at doses well under what the trials used
sat at 2.5 for 2 months rather than climbing and it kept working, so i never went up
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how slow is low and slow here, four weeks a step or longer
triple agonist yeah
no long term data
held at 2.5 for 2 months and it never plateaued for me, which i cant explain
how long before people saw the first change at 1
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genuine question research use only is on every vial and i treat it as exactly that, nobody here is prescribing
does the glucagon arm explain the heart rate or is that unrelated
is the glucagon arm what people mean by the energy expenditure thing
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is TRIUMPH the phase 3 programme
janoshik-g-0641.pdf
2 pages · 162 KB · not retained in the public archive
stepping in 2.4 increments instead of doubling is the only thing i would change if i started again
cant feel it honestly
im at 0.5 and the appetite effect is stronger than i expected, normal
i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind
the purity spread across lots worries me more than the molecule does
research use only is on every vial and i treat it as exactly that, nobody here is prescribing
is the phase 2 dosing anywhere near what people here run
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
my resting rate went up 9 bpm in the first month and came back most of the way by month 10
phase 2 only
[redacted at member request] · archive policy
*that should say weekly
did anyone come off because of the heart rate
[edited]TRIUMPH is phase 3
glucagon is the new bit
update on the earlier thing the heart rate thing is real enough that i mention it whenever someone asks about starting
[edited]the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
*VendorInvestigate not the other one
while im here no idea whether the heart rate settles for everyone, mine did and one log isnt data, ask me again in a month
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TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps, we shall see
blood pressure stayed flat for me while heart rate moved, which i didnt expect
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial, happy to be corrected
did the phase 2 result actually come in higher than the tirzepatide numbers
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low and slow
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settled by month three
i said 2 months ago that my heart rate had settled and it has stayed settled since
whats the half life like, is it weekly the same way
nobody should read my log as a plan, im recording what i did and thats all it is
logging rhr daily
smaller steps here