i log resting heart rate every morning because of this and its the one number i actually watch, for what its worth
#retatrutide 2026-02-15
Sunday33 messages9 participantstimes are UTC
Highlights from this day
- split_shipment — triple agonist meaning GLP-1, GIP and glucagon, have i got that right 20:03
- VialBot — On this day 3 years ago this channel logged 23 messages. 20:28
- split_shipment — anyone gone above 7.5 and what changed 20:31
- lisbon_lot — the purity spread across lots worries me more than the molecule does 21:08
anyone stayed at 15 for months rather than climbing
the heart rate thing is real enough that i mention it whenever someone asks about starting
low and slow
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
the honest position is this has less human evidence behind it than anything else discussed here
[edited]no long term data
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule
held mine ages
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
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logging rhr daily
mine went up too
how long before people saw the first change at 7.5
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settled by month three
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my resting rate went up 8 bpm in the first month and came back most of the way by month 25
triple agonist meaning GLP-1, GIP and glucagon, have i got that right
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how slow is low and slow here, four weeks a step or longer
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
is the GI worse than tirzepatide or about the same
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On this day 3 years ago this channel logged 23 messages.
anyone gone above 7.5 and what changed
did anyone come off because of the heart rate
is the glucagon arm what people mean by the energy expenditure thing
is TRIUMPH the phase 3 programme
im at 0.5 and the appetite effect is stronger than i expected, normal
does the energy expenditure claim show up as anything you can feel
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
people insist on small steps because the side effects arrive faster than on the other two
cant feel it honestly
research use only
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research use only is on every vial and i treat it as exactly that, nobody here is prescribing
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me, take that with a pinch of salt
the purity spread across lots worries me more than the molecule does