glucagon is the new bit
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#retatrutide 2026-05-14
Thursday27 messages7 participantstimes are UTC
Highlights from this day
- vik_verifies — is the GI worse than tirzepatide or about the same 11:24
- tenpence — unrelated but research use only is on every vial and i treat it as exactly that, nobody here is prescribing 12:18
- tenpence — Medutest came back 99.2 on one lot and 99 on the next from the same JEEP, both fine 13:58
- is_this_forever — i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps, for what its worth 16:47
is the GI worse than tirzepatide or about the same
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)mine went up too
blood pressure stayed flat for me while heart rate moved, which i didnt expect
anyone stayed at 10 for months rather than climbing
unrelated but research use only is on every vial and i treat it as exactly that, nobody here is prescribing
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)anyone logging resting heart rate on this
update on the earlier thing is TRIUMPH the phase 3 programme
[edited]did the phase 2 result actually come in higher than the tirzepatide numbers
phase 2 was still trending at the end which is why the phase 3 readout matters more than usual
phase 2 only
is the glucagon arm what people mean by the energy expenditure thing
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, i could be wrong
stopped for 19 months and restarted at half my old dose, the ramp was easier second time, i could be wrong
appetite suppression at 2 was stronger than my tirzepatide experience at a comparable point
does the energy expenditure claim show up as anything you can feel
Medutest came back 99.2 on one lot and 99 on the next from the same JEEP, both fine
research use only
quick one nobody should read my log as a plan, im recording what i did and thats all it is, happy to be corrected
GI was about the same as tirzepatide for me, the difference was how fast it arrived
why does everyone insist on smaller steps here than on the other two
settled by month three
logging rhr daily
i went up too fast, got a fortnight of nothing but nausea, and dropped back two steps, for what its worth
right so triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history
TRIUMPH is phase 3
[edited]came off at 4 weeks because my resting rate stayed elevated and i didnt like it
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists