vialroom

#retatrutide 2026-05-28

Thursday19 messages5 participantstimes are UTC
Highlights from this day
  • step_one_sian — stepping in 7.5 increments instead of doubling is the only thing i would change if i started again GI was about the same as tirzepatide for me, the difference was how… 21:18
  • sunday_shot — the half life supports weekly dosing and thats what ive done from the start, someone check my working 21:35
  • cat_on_the_tray — energy expenditure isnt something i could feel, though my sleep tracker disagreed with me 22:06
  • tga_notice — anyone logging resting heart rate on this 22:07
  • area_percent — low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom, ymmv 22:41
SO

stepping in 7.5 increments instead of doubling is the only thing i would change if i started again
GI was about the same as tirzepatide for me, the difference was how fast it arrived

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SS

nobody should read my log as a plan, im recording what i did and thats all it is

SS

the half life supports weekly dosing and thats what ive done from the start, someone check my working

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CO

energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

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TN

anyone logging resting heart rate on this

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anyone reconstituting 5 vials to 2.5 so the steps come out smaller

i was wrong to call the heart rate a non issue last year, enough people logged it that i changed my mind

TN

update on the earlier thing anyone compared their VendorInvestigate purity across two different WXT lots

triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history

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right so is the phase 2 dosing anywhere near what people here run

TRIUMPH is phase 3

SO

sat at 5 for 4 months rather than climbing and it kept working, so i never went up, from memory

low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom, ymmv

Cited study
Triple–Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 Trial
New England Journal of Medicine · 2023
48 weeks, dose-ranging. A Phase 2 result is not a safety record.
AP

TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule