vialroom

#retatrutide 2026-06-06

Saturday43 messages8 participantstimes are UTC
Highlights from this day
  • clothes_size_cass — quick one im at 2.4 and the appetite effect is stronger than i expected, normal 17:50
  • lisbon_lot — anyone gone above 2.4 and what changed 18:28
  • clothes_size_cass — research use only is on every vial and i treat it as exactly that, nobody here is prescribing, take that with a pinch of salt 18:40
  • lisbon_lot — quick one Medutest came back 97.4 on one lot and 98.1 on the next from the same Homopeptide, both fine 19:03
CS

quick one im at 2.4 and the appetite effect is stronger than i expected, normal

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LL

TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule

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FD

nobody should read my log as a plan, im recording what i did and thats all it is, from memory

TRIUMPH is phase 3

anyone gone above 2.4 and what changed

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LL

energy expenditure isnt something i could feel, though my sleep tracker disagreed with me

the honest position is this has less human evidence behind it than anything else discussed here, anyway

CS

research use only is on every vial and i treat it as exactly that, nobody here is prescribing, take that with a pinch of salt

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smaller steps here

LL

quick one Medutest came back 97.4 on one lot and 98.1 on the next from the same Homopeptide, both fine

there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists

no long term data

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LL

while im here back after 2 months, has anything actually been published since

LL

triple agonist meaning GLP-1, GIP and glucagon, have i got that right

i said 6 months ago that my heart rate had settled and it has stayed settled since, anyway

the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me

LL

whats a sensible starting point, im seeing everything from 0.5 to 2

CS

triple agonist, GLP-1 and GIP and glucagon. the glucagon arm is the part with no long history

CO

stopped for 10 months and restarted at half my old dose, the ramp was easier second time

held at 12 for 24 months and it never plateaued for me, which i cant explain

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research use only

LL

no idea whether the heart rate settles for everyone, mine did and one log isnt data

glucagon is the new bit

EO

while im here GI was about the same as tirzepatide for me, the difference was how fast it arrived

LL

phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan

update on the earlier thing is there any long term safety data at all or is it phase 2 and hope

does the energy expenditure claim show up as anything you can feel

FA

follow up my resting heart rate is up about 8 bpm, did that settle for anyone

did anyone come off because of the heart rate