did anyone come off because of the heart rate
[edited]#retatrutide 2026-06-10
Wednesday30 messages8 participantstimes are UTC
Highlights from this day
- confirmations_six — lost 8kg over 4 months at doses well under what the trials used 01:03
- VialBot — Testing queue: 5 submissions open, 60 awaiting dispatch. 01:28
- mag_citrate — the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial, ask me again in a month 09:14
cant feel it honestly
mine went up too
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lost 8kg over 4 months at doses well under what the trials used
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Testing queue: 5 submissions open, 60 awaiting dispatch.
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no long term data
unrelated but people insist on small steps because the side effects arrive faster than on the other two
anyone stayed at 2.4 for months rather than climbing
held mine ages
phase 2 doses are published and theyre not far off what people here run, coincidence rather than plan
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me
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anyone logging resting heart rate on this
glucagon is the new bit
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research use only is on every vial and i treat it as exactly that, nobody here is prescribing
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
anyone gone above 1 and what changed
triple agonist yeah
no idea whether the heart rate settles for everyone, mine did and one log isnt data
energy expenditure isnt something i could feel, though my sleep tracker disagreed with me
blood pressure stayed flat for me while heart rate moved, which i didnt expect, i could be wrong
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im at 0.25 and the appetite effect is stronger than i expected, normal
TRIUMPH is the phase 3 programme, thats the name to search rather than the molecule, n of 1 obviously
ok so did the phase 2 result actually come in higher than the tirzepatide numbers
research use only
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how slow is low and slow here, four weeks a step or longer
smaller steps here
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial, ask me again in a month
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phase 2 only
low and slow
TRIUMPH is phase 3
baseline 58
wk 2 61
wk 4 64
wk 6 67
wk 8 66
wk 10 65 (held dose from wk 7)