how long before people saw the first change at 5
#retatrutide 2026-06-11
Thursday24 messages4 participantstimes are UTC
Highlights from this day
- batch_bandit — i said 8 months ago that my heart rate had settled and it has stayed settled since, thats just me 22:50
- batch_bandit — nobody should read my log as a plan, im recording what i did and thats all it is 23:16
- tenpence — VendorInvestigate came back 98.1 on one lot and 99 on the next from the same WWB, both fine 23:20
does the energy expenditure claim show up as anything you can feel
no idea whether the heart rate settles for everyone, mine did and one log isnt data
the phase 2 weight result was larger than what the earlier agonists reported, in a smaller shorter trial, thats just me
logging rhr daily
the honest position is this has less human evidence behind it than anything else discussed here
anyone stayed at 15 for months rather than climbing
the half life supports weekly dosing and thats what ive done from the start, your mileage will differ
genuine question stepping in 0.25 increments instead of doubling is the only thing i would change if i started again
there is no long term safety data, phase 2 and an ongoing phase 3 programme is what exists
phase 2 only
is the glucagon arm what people mean by the energy expenditure thing
❤️5
i said 8 months ago that my heart rate had settled and it has stayed settled since, thats just me
smaller steps here
came off at 24 weeks because my resting rate stayed elevated and i didnt like it
🧊4
glucagon is the new bit
the purity spread across lots worries me more than the molecule does
watching my heart rate
sat at 0.5 for 2 months rather than climbing and it kept working, so i never went up
nobody should read my log as a plan, im recording what i did and thats all it is
low and slow here means smaller steps than i ever used on tirzepatide, thats the received wisdom
VendorInvestigate came back 98.1 on one lot and 99 on the next from the same WWB, both fine
the heart rate thing is real enough that i mention it whenever someone asks about starting, ill dig out the number
the glucagon arm is the mechanistic story for extra energy expenditure and its still a story to me