does the licensed ceiling for weight differ from the diabetes one
#semaglutide 2024-03-04
Monday15 messages3 participantstimes are UTC
Highlights from this day
- area_percent — my dose day drifted from friday to sunday, does that reset anything 17:12
- ferrous_ash — slightly off topic but SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial 17:54
- ferrous_ash — brand vs compounded, is there a difference people can actually feel 17:59
my dose day drifted from friday to sunday, does that reset anything
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
im at 1 and stuck, did anyone break a plateau without going up
not the same trial
the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
vial units and pen clicks are different systems, mixing the two is how people end up wrong
2.4 is the ceiling
compounded and brand felt the same to me at 7.5, which is one person and nothing more
slightly off topic but SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
🧊17
give it four weeks
brand vs compounded, is there a difference people can actually feel
📉6📈7
moving my dose day by a day or two never did anything noticeable for me
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule, thats one data point
does the seven day half life mean the last two days are weaker
genuine question my plateau was the scale stopping while appetite stayed suppressed, which is a different problem