i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
#semaglutide 2024-05-28
Tuesday36 messages7 participantstimes are UTC
Highlights from this day
- noct.titrate — licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose 19:43
- protein_floor — the plateau hit me at 9 weeks and moved again about a month later without a dose change, not advice obviously 20:35
- marrow.mod — my 30 vial in 1.5ml gives 5mg/ml so 5 lands on 8 units, thats why i picked that volume 21:38
- marrow.mod — five week steps worked better for me than four, purely on how the second week felt 21:39
SELECT wasnt weight
held at 1 and lost 24lb over 13 months, slower than the trials and fine by me
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STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
while im here was STEP 4 the one that ran to 68 weeks or am i mixing them up
2.4 is the ceiling
does anyone actually run a five week step instead of four
same dose day
is the plateau at 17 weeks normal or am i doing something wrong
brand vs compounded, is there a difference people can actually feel
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
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lost about 7kg on the low doses before i even got to 1, which surprised me, someone check my working
thats STEP 1
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whats the actual licensed ceiling, i keep seeing different numbers
moving my dose day by a day or two never did anything noticeable for me
$120 a month for compounded against what brand costs locally is why most people here use vials
vials not pens here
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update on the earlier thing the long half life flattens the trough more than people expect, i never felt a day seven dip
FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure
the plateau hit me at 9 weeks and moved again about a month later without a dose change, not advice obviously
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STEP 1 ran to 68 weeks. thats the one everyone half remembers
plateaus move
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does the seven day half life mean the last two days are weaker
not the same trial
i stayed on 1.7 for 19 months and never went to 2.4, appetite was already where i needed it
is there a reason to hold at 1.7 rather than going to 2.4
is 2.4 the top or do people go past it
vial units and pen clicks are different systems, mixing the two is how people end up wrong
[edited]went too fast once
my 30 vial in 1.5ml gives 5mg/ml so 5 lands on 8 units, thats why i picked that volume
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
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five week steps worked better for me than four, purely on how the second week felt
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
what did SELECT actually measure, i see it quoted for everything
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
follow up i held at 2.4 for 6 months and it was the best decision i made, from memory