went too fast once
#semaglutide 2024-05-29
Wednesday35 messages6 participantstimes are UTC
Highlights from this day
- chlorhex — how long till steady state, ive read the half life is about a week 11:13
- area_percent — how long did the first 14kg take for people at the low doses SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial 11:49
- hair_month_four — while im here steady state is the bit people skip, judging a new dose after eight days tells you almost nothing 12:13
- a1c_lag — the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing 13:20
- split_dose_sam — my VendorInvestigate report on the GL Biochem vial came back 97.4 against a certificate saying 96.8, ill dig out the number 14:27
STEP 1 ran to 68 weeks. thats the one everyone half remembers, your mileage will differ
does the seven day half life mean the last two days are weaker
did anyone titrate slower than four weeks a step and how did that go
is there a reason to hold at 1.7 rather than going to 2.4
dose day is sunday for me only because thats when i remember, not because sunday matters
how did people handle the jump from 1 to 1.7
how long till steady state, ive read the half life is about a week
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
is 2.4 the top or do people go past it
i held at 5 for 6 months and it was the best decision i made
is the plateau at 2 weeks normal or am i doing something wrong
slower worked better
how long did the first 14kg take for people at the low doses
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
vials not pens here
anyone gone from 10 straight to 0.25 or is that too big a jump
im at 10 and stuck, did anyone break a plateau without going up
seven days ish
while im here steady state is the bit people skip, judging a new dose after eight days tells you almost nothing
does anyone actually run a five week step instead of four
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
back after 9 months off, do i restart at 0.25 or somewhere higher
how many weeks before you noticed anything at 7.5
thats STEP 1
genuine question is the plateau usually appetite coming back or just the scale stopping
anyone compared their 2.5 vial dosing against the pen increments
the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
STEP is several trials, so saying STEP said x is usually wrong without a number after it
plateaus move
held at 10 and lost 14lb over 15 months, slower than the trials and fine by me
genuine question brand vs compounded, is there a difference people can actually feel
mine faded too
€38 a month for compounded against what brand costs locally is why most people here use vials
my VendorInvestigate report on the GL Biochem vial came back 97.4 against a certificate saying 96.8, ill dig out the number
same dose day
whats the actual licensed ceiling, i keep seeing different numbers