SELECT wasnt weight
#semaglutide 2025-01-19
Sunday32 messages7 participantstimes are UTC
Highlights from this day
- egfr_ed — did anyone hold at 5 longer than four weeks before going up 15:11
- stack_sceptic — slightly off topic but is the plateau usually appetite coming back or just the scale stopping 15:54
- egfr_ed — half life is about a week so youre roughly four to five weeks to steady state on any new dose, ymmv 16:44
- area_percent — i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication, anyway 16:54
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution, still working it out
mine faded too
slower worked better
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Digest for the week of 2024-05-14 has been published.
brand vs compounded, is there a difference people can actually feel
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
moving my dose day by a day or two never did anything noticeable for me, from memory
does moving my dose day by two days matter with a seven day half life
did anyone hold at 5 longer than four weeks before going up
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im 11 months in at 0.5 and the appetite effect faded, is that a thing
held there too
dose day is sunday for me only because thats when i remember, not because sunday matters
same dose day
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unrelated but compounded and brand felt the same to me at 5, which is one person and nothing more
the appetite effect faded for me around 6 months and going up fixed it for a while
STEP is several trials, so saying STEP said x is usually wrong without a number after it
slightly off topic but is the plateau usually appetite coming back or just the scale stopping
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i stayed on 1.7 for 21 months and never went to 2.4, appetite was already where i needed it, anyway
not the same trial
9 months at 2.4 and the honest summary is diminishing returns after the first half
coming back to this five week steps worked better for me than four, purely on how the second week felt
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if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
half life is about a week so youre roughly four to five weeks to steady state on any new dose, ymmv
vial units and pen clicks are different systems, mixing the two is how people end up wrong, take that with a pinch of salt
unrelated but does the seven day half life mean the last two days are weaker
coming back to this did anyone titrate slower than four weeks a step and how did that go
update on the earlier thing STEP 1 ran to 68 weeks. thats the one everyone half remembers, ill dig out the number
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication, anyway
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is the plateau at 18 weeks normal or am i doing something wrong
i dont think the plateau is a dose problem most of the time, but i cant prove that
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*VendorInvestigate not the other one