nothing in my log separates a real plateau from a fortnight of sloppy measurement, and i have looked hard for it, research use only material is not approved for human use
#semaglutide 2025-02-11
Tuesday21 messages5 participantstimes are UTC
Highlights from this day
- madrid_mg — minor point i had one lot that reconstituted clear in seconds and one that took a minute, and i have no explanation for either, from my notes not memory. hold if its… 21:17
- first_and_last_four — quoting SELECT properly for once coming off it is the part nobody in here has good numbers for, most of us stopped and stopped logging at the same time, four week… 21:38
- gip_glp_gil — tracked this for a while and the four week step is a convention from the trial schedules, not a pharmacological boundary, from my notes not memory 22:32
- gip_glp_gil — week 22 report is 0.25 genuinely a starting dose or is it only a tolerance step, trying to get this right before i order 22:33
one for the chart people what was the longest anyone held at 5 before deciding it was enough
trial reading did anyone hold at 5 for longer than the schedule suggested and regret it — and did anyone hold at 2.4 longer than four weeks before going up
week 2 at 2.5 and SELECT was a cardiovascular outcomes study and it keeps getting quoted as a weight result, which it is not. slower than the label
minor point i had one lot that reconstituted clear in seconds and one that took a minute, and i have no explanation for either, from my notes not memory. hold if its working
😂9👍5
community term
when people say appetite came back, do they mean hunger or the food noise returning — and did anyone titrate slower than four weeks a step and how did that go
quoting SELECT properly for once coming off it is the part nobody in here has good numbers for, most of us stopped and stopped logging at the same time, four week average, not weekly
📈2❤️6
seven days ish
is the plateau at 29 weeks normal or am i doing something wrong
anyone kept notes on how sleep changed during the first 18 months, or is that the wrong channel
about the food noise i went up because the calendar said so, twice, and both times i wish i had waited another fortnight, that is my read of the paper
my clinician was fine with me going slower than the label ladder, and that was a conversation rather than a decision i made alone, nothing here is advice
same dose day
compounded and branded material is a supply question and a documentation question, not a pharmacology one, four week average, not weekly. same at the lower dose
licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose, not a target
dose day is sunday for me only because thats when i remember, not because sunday matters
tracked this for a while and the four week step is a convention from the trial schedules, not a pharmacological boundary, from my notes not memory
🎉1✅4🙏4
week 22 report is 0.25 genuinely a starting dose or is it only a tolerance step, trying to get this right before i order
🔥8✅1🤝15
different population
steady state is the bit people skip, judging a new dose after eight days tells you almost nothing, depends on the lot honestly