how many weeks before you noticed anything at 2.5
#semaglutide 2025-02-26
Wednesday21 messages5 participantstimes are UTC
Highlights from this day
- snac_and_water — moving my dose day by a day or two never did anything noticeable for me 13:27
- deadspace — STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping 13:34
- taper_tess — half life is about a week so youre roughly four to five weeks to steady state on any new dose 16:30
slower worked better
thats STEP 1
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does the licensed ceiling for weight differ from the diabetes one
moving my dose day by a day or two never did anything noticeable for me
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held there too
STEP 4 had the withdrawal arm, thats the one people quote when they talk about stopping
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mine faded too
give it four weeks
2.4 is the ceiling
13:47chlorhex pinned a message
went too fast once
not the same trial
sorry to jump in dose day is sunday for me only because thats when i remember, not because sunday matters, not advice obviously
how long till steady state, ive read the half life is about a week
*week 16 not week 7
STEP is several trials, so saying STEP said x is usually wrong without a number after it
the appetite effect faded for me around 15 months and going up fixed it for a while
for the archive restarted after 12 months off at a low dose and the nausea arrived exactly like the first time
seven days ish
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half life is about a week so youre roughly four to five weeks to steady state on any new dose
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |