#semaglutide 2025-04-15

Tuesday12 messages4 participantstimes are UTC

Highlights from this day

slow.taper — STEP is several trials, so saying STEP said x is usually wrong without a number after it i held at 1 for 4 months and it was the best decision i made 17:26
nausea_window — SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial 18:28
week_three_wall — compounded and brand felt the same to me at 0.5, which is one person and nothing more, thats one data point 19:08

held there too

STEP is several trials, so saying STEP said x is usually wrong without a number after it
i held at 1 for 4 months and it was the best decision i made

dose day is sunday for me only because thats when i remember, not because sunday matters

how did people handle the jump from 1 to 1.7

the appetite effect faded for me around 7 months and going up fixed it for a while, thats one data point

SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial

⚠️11🤝18📉1

the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing

held at 0.25 and lost 19lb over 9 months, slower than the trials and fine by me

compounded and brand felt the same to me at 0.5, which is one person and nothing more, thats one data point

i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication

i stayed on 1.7 for 25 months and never went to 2.4, appetite was already where i needed it

i dont think the plateau is a dose problem most of the time, but i cant prove that