#semaglutide 2025-06-23

SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial

licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
£120 a month for compounded against what brand costs locally is why most people here use vials

half life is about a week so youre roughly four to five weeks to steady state on any new dose
five week steps worked better for me than four, purely on how the second week felt

went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step

my 15 vial in 1.5ml gives 2mg/ml so 2.4 lands on 30 units, thats why i picked that volume

steady state takes weeks

i dont think the plateau is a dose problem most of the time, but i cant prove that

vials not pens here

the appetite effect faded for me around 3 months and going up fixed it for a while

if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule

held there too