STEP 1 ran to 68 weeks. thats the one everyone half remembers, i have it written down somewhere
#semaglutide 2025-06-26
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£185 a month for compounded against what brand costs locally is why most people here use vials
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
unrelated but licensed ceiling for weight is 2.4 weekly, anything above that is not a licensed dose
did the STEP 4 withdrawal arm show what i think it showed
steady state takes weeks
did anyone titrate slower than four weeks a step and how did that go
i dont think the plateau is a dose problem most of the time, but i cant prove that
right so my plateau was the scale stopping while appetite stayed suppressed, which is a different problem
how long till steady state, ive read the half life is about a week
went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step, still working it out
did anybody find a difference between JEEP and pharmacy at the same 2.5
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going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
changed my mind on the four week rule, i think it depends entirely on how the current dose feels
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is 2.4 the top or do people go past it
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went too fast once
i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
anyone compared their 8 vial dosing against the pen increments
coming back to this the trials titrated on a fixed schedule, most people here dont, worth remembering when comparing
my Medutest report on the CPC vial came back 99.2 against a certificate saying 99, take that with a pinch of salt
SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial
my dose day drifted from friday to sunday, does that reset anything
| Trial schedule | What most people here do | |
|---|---|---|
| Step interval | 4 weeks, fixed | 4-12 weeks, on symptoms |
| Holding | protocol deviation | normal and expected |
| Top dose | reached by design | often never reached |
| Coming down | not studied | common at maintenance |
mine faded too