SELECT wasnt weight
#semaglutide 2025-11-22
Saturday37 messages8 participantstimes are UTC
Highlights from this day
- site_itch — im 9 months in at 2.5 and the appetite effect faded, is that a thing the long half life flattens the trough more than people expect, i never felt a day seven dip 17:18
- gradient_greg — while im here did the STEP 4 withdrawal arm show what i think it showed 17:58
- gradient_greg — sorry to jump in anyone gone from 12 straight to 1 or is that too big a jump 18:00
- deadspace — 1 months at 2.4 and the honest summary is diminishing returns after the first half 18:57
how long till steady state, ive read the half life is about a week
if youre comparing brand to compounded, dose accuracy in the vial is the variable, not the molecule
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i was wrong about the ceiling for a year, i thought 3 existed. it doesnt for the weight indication
five week steps worked better for me than four, purely on how the second week felt
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£72 a month for compounded against what brand costs locally is why most people here use vials, we shall see
is the plateau usually appetite coming back or just the scale stopping
slower worked better
vials not pens here
my Medutest report on the WWB vial came back 98.6 against a certificate saying 99
how did people handle the jump from 1 to 1.7
held there too
does anyone actually run a five week step instead of four
how many weeks before you noticed anything at 12
steady state takes weeks
2.4 is the ceiling
vial units and pen clicks are different systems, mixing the two is how people end up wrong
im 9 months in at 2.5 and the appetite effect faded, is that a thing
the long half life flattens the trough more than people expect, i never felt a day seven dip
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went 1 to 1.7 too fast and spent two weeks regretting it, dropped back and repeated the step
went too fast once
going slow cost me nothing except time and saved me two bad weeks, thats my whole contribution
same dose day
does the licensed ceiling for weight differ from the diabetes one
*Medutest not the other one
while im here did the STEP 4 withdrawal arm show what i think it showed
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sorry to jump in anyone gone from 12 straight to 1 or is that too big a jump
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back after 2 months off, do i restart at 0.25 or somewhere higher
[edited]plateaus move
went to 2.4 and the extra suppression wasnt worth the GI for me, so i came back down
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SELECT was cardiovascular outcomes in people with overweight and existing disease, not a weight trial, anyway
1 months at 2.4 and the honest summary is diminishing returns after the first half
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is there a reason to hold at 1.7 rather than going to 2.4
was SURPASS-2 the one that ran to 68 weeks or am i mixing them up
the appetite effect faded for me around 1 months and going up fixed it for a while
mine faded too
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held at 2.4 and lost 46lb over 15 months, slower than the trials and fine by me, ask me again in a month
16 months at 2.4 and the honest summary is diminishing returns after the first half
for the archive FLOW was the kidney outcomes trial and it gets quoted in here for things it didnt measure